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1

[Current Topics in Microbiology and Immunology] || CTLA-4, an Essential Immune-Checkpoint for T-Cell Activation

Chikuma, Shunsuke

Year:

2017

Language:

english

File:

PDF, 520 KB

english, 2017

2

Negative Regulation of Cytokine Signaling in Immunity

Yoshimura, Akihiko, Ito, Minako, Chikuma, Shunsuke, Akanuma, Takashi, Nakatsukasa, Hiroko

Journal:

Cold Spring Harbor Perspectives in Biology

Year:

2017

Language:

english

File:

PDF, 752 KB

english, 2017

3

A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application

Okazaki, Taku, Chikuma, Shunsuke, Iwai, Yoshiko, Fagarasan, Sidonia, Honjo, Tasuku

Journal:

Nature Immunology

Year:

2013

Language:

english

File:

PDF, 633 KB

english, 2013

4

The expression of differentiation markers in aquaporin-3 deficient epidermis

Mariko Hara-Chikuma, Kenzo Takahashi, Shunsuke Chikuma, A. S. Verkman, Yoshiki Miyachi

Journal:

Archives of Dermatological Research

Year:

2009

Language:

english

File:

PDF, 536 KB

english, 2009

5

Successful Gene Therapy via Intraarticular Injection of Adenovirus Vector Containing CTLA4IgG in a Murine Model of Type II Collagen-Induced Arthritis

Ijima, Kenichi, Murakami, Masaaki, Okamoto, Hiroshi, Inobe, Manabu, Chikuma, Shunsuke, Saito, Izumu, Kanegae, Yumi, Kawaguchi, Yoshinori, Kitabatake, Akira, Uede, Toshimitsu

Journal:

Human Gene Therapy

Year:

2001

Language:

english

File:

PDF, 1.38 MB

english, 2001

6

Tyrosine 201 of the cytoplasmic tail of CTLA-4 critically affects T regulatory cell suppressive function

Stumpf, Melanie, Zhou, Xuyu, Chikuma, Shunsuke, Bluestone, Jeffrey A.

Journal:

European Journal of Immunology

Year:

2014

Language:

english

File:

PDF, 858 KB

english, 2014

7

Reprogramming of Th1 cells into regulatory T cells through rewiring of the metabolic status

Kanamori, Mitsuhiro, Nakatsukasa, Hiroko, Ito, Minako, Chikuma, Shunsuke, Yoshimur, Akihiko

Journal:

International Immunology

Year:

2018

Language:

english

File:

PDF, 6.32 MB

english, 2018

8

Generation of allo-antigen-specific induced Treg stabilized by vitamin C treatment and its application for prevention of acute graft versus host disease model

Kasahara, Hidenori, Kondo, Taisuke, Nakatsukasa, Hiroko, Chikuma, Shunsuke, Ito, Minako, Ando, Makoto, Kurebayashi, Yutaka, Sekiya, Takashi, Yamada, Taketo, Okamoto, Shinichiro, Yoshimura, Akihiko

Journal:

International Immunology

Year:

2017

Language:

english

File:

PDF, 3.40 MB

english, 2017

9

CTLA-4 and tolerance

Shunsuke Chikuma, Jeffrey A. Bluestone

Journal:

Immunologic Research

Year:

2003

Language:

english

File:

PDF, 220 KB

english, 2003

10

Impairment of NK Cell Function by NKG2D Modulation in NOD Mice

Kouetsu Ogasawara, Jessica A Hamerman, Honor Hsin, Shunsuke Chikuma, Helene Bour-Jordan, Taian Chen, Thomas Pertel, Claude Carnaud, Jeffrey A Bluestone, Lewis L Lanier

Journal:

Year:

2003

Language:

english

File:

PDF, 646 KB

english, 2003

11

TRIM28 prevents autoinflammatory T cell development in vivo

Chikuma, Shunsuke, Suita, Naomasa, Okazaki, Il-Mi, Shibayama, Shiro, Honjo, Tasuku

Journal:

Nature Immunology

Year:

2012

Language:

english

File:

PDF, 1.05 MB

english, 2012

12

Involvement of CD28/CTLA4-B7 Costimulatory Pathway in the Development of Lymphadenopathy and Splenomegaly in MRL/lpr Mice.

TAKIGUCHI, Mitsuyoshi, MURAKAMI, Masaaki, NAKAGAWA, Izumi, Misanur RASHID, Mohammod, TOSA1, Noriko, CHIKUMA, Shunsuke, HASHIMOTO, Akira, UEDE, Toshimitsu

Journal:

Journal of Veterinary Medical Science

Year:

2000

Language:

english

File:

PDF, 116 KB

english, 2000

13

Long-Term Acceptance of Allografts by in Vivo Gene Transfer of Regulatable Adenovirus Vector Containing CTLA4IgG and loxP

Takehara, Megumi, Murakami, Masaaki, Inobe, Manabu, Tanaka, Kumiko, Chikuma, Shunsuke, Saito, Izumu, Kanegae, Yumi, Yasunami, Yohichi, Nakano, Masahiko, Yamashita, Kenichiro, Todo, Satoru, Uede, Toshi

Journal:

Human Gene Therapy

Year:

2001

Language:

english

File:

PDF, 904 KB

english, 2001

14

Generation and application of human induced-stem cell memory T cells for adoptive immunotherapy

Kondo, Taisuke, Imura, Yuki, Chikuma, Shunsuke, Hibino, Sana, Omata-Mise, Setsuko, Ando, Makoto, Akanuma, Takashi, Iizuka, Mana, Sakai, Ryota, Morita, Rimpei, Yoshimura, Akihiko

Journal:

Year:

2018

Language:

english

File:

PDF, 1.38 MB

english, 2018

15

Tocilizumab monotherapy uncovered the role of the CCL22/17âCCR4 + Treg axis during remission of crescentic glomerulonephritis

Sakai, Ryota, Ito, Minako, Yoshimoto, Keiko, Chikuma, Shunsuke, Kurasawa, Takahiko, Kondo, Tsuneo, Suzuki, Katsuya, Takeuchi, Tsutomu, Amano, Koichi, Yoshimura, Akihiko

Journal:

Clinical & Translational Immunology

Year:

2020

File:

PDF, 2.31 MB

2020

16

Suppressive effect of clozapine but not haloperidol on the increases of neuropeptide-degrading enzymes and glial cells in MK-801-treated rat brain regions

Mohammad Arif, Toshiyuki Chikuma, Md. Mahiuddin Ahmed, Shunsuke Yoshida, Takeshi Kato

Journal:

Neuroscience Research

Year:

2007

Language:

english

File:

PDF, 2.20 MB

english, 2007

17

Innate-like function of memory Th17 cells for enhancing endotoxin-induced acute lung inflammation through IL-22

Sakaguchi, Ryota, Chikuma, Shunsuke, Shichita, Takashi, Morita, Rimpei, Sekiya, Takashi, Ouyang, Wenjun, Ueda, Tomomi, Seki, Hiroyuki, Morisaki, Hiroshi, Yoshimura, Akihiko

Journal:

International Immunology

Year:

2015

Language:

english

File:

PDF, 727 KB

english, 2015

18

Antibodies to different peptides in osteopontin reveal complexities in the various secreted forms

Shigeyuki Kon, Masahiro Maeda, Tatsuya Segawa, Yoshiaki Hagiwara, Yuko Horikoshi, Shunsuke Chikuma, Kumiko Tanaka, Mohammod Mizanur Rashid, Manabu Inobe, Ann F. Chambers, Toshimitsu Uede

Journal:

Journal of Cellular Biochemistry

Year:

2000

Language:

english

File:

PDF, 332 KB

english, 2000

19

Blockage of Core Fucosylation Reduces Cell-Surface Expression of PD-1 and Promotes Anti-tumor Immune Responses of T Cells

Okada, Masahiro, Chikuma, Shunsuke, Kondo, Taisuke, Hibino, Sana, Machiyama, Hiroaki, Yokosuka, Tadashi, Nakano, Miyako, Yoshimura, Akihiko

Journal:

Year:

2017

Language:

english

File:

PDF, 3.83 MB

english, 2017

20

Activation-Induced Cytidine Deaminase Expression in CD4+ T Cells is Associated with a Unique IL-10-Producing Subset that Increases with Age

Qin, Hongyan, Suzuki, Keiichiro, Nakata, Mikiyo, Chikuma, Shunsuke, Izumi, Nakako, Thi Huong, Le, Maruya, Mikako, Fagarasan, Sidonia, Busslinger, Meinrad, Honjo, Tasuku, Nagaoka, Hitoshi, Ahuja, Sunil

Journal:

Year:

2011

Language:

english

File:

PDF, 1.20 MB

english, 2011

21

Suppressors of cytokine signaling: Potential immune checkpoint molecules for cancer immunotherapy

Chikuma, Shunsuke, Kanamori, Mitsuhiro, Mise-Omata, Setsuko, Yoshimura, Akihiko

Journal:

Year:

2017

Language:

english

File:

PDF, 982 KB

english, 2017

22

Role of scavenger receptors as damage-associated molecular pattern receptors in Toll-like receptor activation

Komai, Kyoko, Shichita, Takashi, Ito, Minako, Kanamori, Mitsuhiro, Chikuma, Shunsuke, Yoshimura, Akihiko

Journal:

International Immunology

Year:

2017

Language:

english

File:

PDF, 996 KB

english, 2017

23

Inhibition of Nr4a receptors enhances anti-tumor immunity by breaking Treg-mediated immune tolerance

Hibino, Sana, Chikuma, Shunsuke, Kondo, Taisuke, Ito, Minako, Nakatsukasa, Hiroko, Omata-Mise, Setsuko, Yoshimura, Akihiko

Journal:

Cancer Research

Year:

2018

Language:

english

File:

PDF, 3.00 MB

english, 2018

24

Approaches for cesium uptake by vermiculite

Suzuki, Noriko, Ozawa, Shunsuke, Ochi, Kotaro, Chikuma, Toshiyuki, Watanabe, Yujiro

Journal:

Journal of Chemical Technology & Biotechnology

Year:

2013

Language:

english

File:

PDF, 114 KB

english, 2013

25

Persistent and Secondary Adenovirus-Mediated Hepatic Gene Expression Using Adenovirus Vector Containing CTLA4IgG

Nakagawa, Izumi, Murakami, Masaaki, Ijima, Kenichi, Chikuma, Shunsuke, Saito, Izumu, Kanegae, Yumi, Ishikura, Hiroshi, Yoshiki, Takashi, Okamoto, Hiroshi, Kitabatake, Akira, Uede, Toshimitsu

Journal:

Human Gene Therapy

Year:

1998

Language:

english

File:

PDF, 4.19 MB

english, 1998

26

Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model

Zhang, Baihao, Chikuma, Shunsuke, Hori, Shohei, Fagarasan, Sidonia, Honjo, Tasuku

Journal:

Proceedings of the National Academy of Sciences

Year:

2016

Language:

english

File:

PDF, 1.28 MB

english, 2016

27

The NOTCH-FOXM1 Axis Plays a Key Role in Mitochondrial Biogenesis in the Induction of Human Stem Cell Memory-like CAR-T Cells

Kondo, Taisuke, Ando, Makoto, Nagai, Nao, Tomisato, Wataru, Srirat, Tanakorn, Liu, Binbin, Mise-Omata, Setsuko, Ikeda, Mari, Chikuma, Shunsuke, Nishimasu, Hiroshi, Nureki, Osamu, Ohmura, Mitsuyo, Haya

Journal:

Cancer Research

Year:

2019

File:

PDF, 2.05 MB

2019

28

Expression of CTLA-4 and FOXP3 in cis protects from lethal lymphoproliferative disease

Shunsuke Chikuma, Jeffrey A. Bluestone

Journal:

European Journal of Immunology

Year:

2007

Language:

english

File:

PDF, 186 KB

english, 2007

29

Basics of PD-1 in self-tolerance, infection, and cancer immunity

Chikuma, Shunsuke

Journal:

International Journal of Clinical Oncology

Year:

2016

Language:

english

File:

PDF, 765 KB

english, 2016

30

Janus kinase 2 is associated with a box 1-like motif and phosphorylates a critical tyrosine residue in the cytoplasmic region of cytotoxic T lymphocyte associated molecule-4

Shunsuke Chikuma, Masaaki Murakami, Kumiko Tanaka, Toshimitsu Uede

Journal:

Journal of Cellular Biochemistry

Year:

2000

Language:

english

File:

PDF, 222 KB

english, 2000

31

Notch-mediated conversion of activated T cells into stem cell memory-like T cells for adoptive immunotherapy

Kondo, Taisuke, Morita, Rimpei, Okuzono, Yuumi, Nakatsukasa, Hiroko, Sekiya, Takashi, Chikuma, Shunsuke, Shichita, Takashi, Kanamori, Mitsuhiro, Kubo, Masato, Koga, Keiko, Miyazaki, Takahiro, Kassai,

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 1.68 MB

english, 2017

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